Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Adrenergic neuron blocking

The answers are 321-cT 322-e, 323-i. (Hardman, pp 238-239, 791.) Reserpine is an adrenergic neuronal blocking agent that causes depletion of central and peripheral stores of NE and dopamine Reserpine acts by irreversibly inhibiting the magnesium-dependent ATP transport process that functions as a carrier for biogenic amines from the cytoplasm... [Pg.195]

An excellent review of the pharmacological actions of adrenergic neurone blocking agents has been given by Boura and Green [10]. The biochemistry of guanethidine itself has been reviewed by Furst [11], with particular emphasis on tissue distribution and metabolism consequently these two topics are not discussed in detail. [Pg.126]

Adrenergic neurone blocking (e.g. xylocholine, guanetHidine) Blocked Blocked Normal Yes No... [Pg.138]

R R Adrenergic neurone blocking activity A n tihypertensive activity... [Pg.141]

Although reduction or abolition of the gross muscarinic stimulation, with retention or enhancement of adrenergic neurone blocking activity, was achieved by suitable modification of the xylocholine molecule, no drug of proven clinical... [Pg.151]

Ar n Adrenergic neurone blocking activity 35% coverage 50% coverage of the eyes of the eyes Ptosis sc ore f Antihypertensive activity... [Pg.153]

The introduction of guanidine [94,138, 252, 254] and quaternary ammonium [94] groups into 2-aminomethyl-l,4-benzodioxan leads to compounds with adrenergic neurone blocking properties similar to those of guanethidine and the... [Pg.155]

Introduction of more than one methyl group into the aromatic ring giving 5,7-, 6,7-, or 5,8-disubstituted compounds, resulted in loss of all activity [94, 138]. The effect of chlorine substitution follows a rather similar pattern [138]. The adrenergic neurone blocking activity of guanoxan is maintained in the homologous compound in which the side chain is increased by one carbon... [Pg.156]

See other pages where Adrenergic neuron blocking is mentioned: [Pg.121]    [Pg.141]    [Pg.67]    [Pg.68]    [Pg.499]    [Pg.73]    [Pg.187]    [Pg.136]    [Pg.137]    [Pg.137]    [Pg.139]    [Pg.140]    [Pg.140]    [Pg.140]    [Pg.141]    [Pg.142]    [Pg.142]    [Pg.142]    [Pg.142]    [Pg.143]    [Pg.146]    [Pg.147]    [Pg.148]    [Pg.149]    [Pg.149]    [Pg.150]    [Pg.151]    [Pg.152]    [Pg.152]    [Pg.152]    [Pg.153]    [Pg.154]    [Pg.154]    [Pg.156]    [Pg.156]    [Pg.158]   


SEARCH



Adrenergic Neurone Blocking Agents

Adrenergic neuron

Adrenergic neuron blocking agents

Adrenergic neuronal-blocking drugs

© 2024 chempedia.info