Adrenaline possible mechanisms

It is believed that the mechanism of action of amphetamines lies in their ability to release epinephrine (adrenaline) and dopamine from presynaptic nerve endings, which stimulate the corresponding receptors in the CNS. It is also possible that they reduce neuronal uptake of amines as well as inhibit their degradation by monoaminoxidase (MAO). Characteristic of this series of compounds is the effect on the respiratory center, on the satiation center located in the hypothalamus, which leads to suppression of feelings of hunger, thus allowing analog of the examined compounds to be used as anorectics. 

A common mechanism may underlie the psychogenic action of the indole type hallucinogens on the one hand and the compounds related to adrenaline on the other, but it is not yet possible to say whether this action is related to 5-hydroxytryptamine or to adrenaline. Adrenochrome and adrenolutin have structural similarities with the indoles and, under similar conditions, both LSD and mescaline similarly antagonize the action of 5-hydroxytryptamine on isolated preparations . There is some evidence that LSD... 

No postulated hormone mechanism of action, with the possible exception of the Sutherland model of glycogenolysis activation by adrenaline, has yet fully satisfied all these criteria. 

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