Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

ADMET properties intestinal permeability

ADMET properties such as solubility, Caco-2 cells permeability, human intestinal... [Pg.388]

Figure 17.1 Correlation of rank order for ADMET Risk and human intestinal absorption (H IA%). The ADMET Risk score ranged from 0 to 5, with 5 being compounds with the greatest risk of having poor ADMET properties. Within a single ADMET Risk number, the compounds were ranked according to ascending estimated human jejunal permeability (ADMET Predictor, Simulations Plus, Inc.). Spearman rank correlation coefficient was 0.7 (pcO.OOl). Figure 17.1 Correlation of rank order for ADMET Risk and human intestinal absorption (H IA%). The ADMET Risk score ranged from 0 to 5, with 5 being compounds with the greatest risk of having poor ADMET properties. Within a single ADMET Risk number, the compounds were ranked according to ascending estimated human jejunal permeability (ADMET Predictor, Simulations Plus, Inc.). Spearman rank correlation coefficient was 0.7 (pcO.OOl).
See other pages where ADMET properties intestinal permeability is mentioned: [Pg.608]    [Pg.55]   
See also in sourсe #XX -- [ Pg.134 , Pg.135 , Pg.161 ]

See also in sourсe #XX -- [ Pg.134 , Pg.135 , Pg.161 ]

See also in sourсe #XX -- [ Pg.161 ]



SEARCH



ADMET

Intestinal permeability

Intestinal properties

Permeability properties

© 2024 chempedia.info