Adipic dialdehyde

Dissolve 7 g. of pure oleic acid in 30 ml. of dry ethyl chloride (chloroform may be used but is less satisfactory), and ozonise at about —30°. Remove the solvent under reduced pressure, dissolve the residue in 50 ml. of dry methyl alcohol and hydrogenate as for adipic dialdehyde in the presence of 0 5 g. of palladium - calcium carbonate. Warm the resulting solution for 30 minutes with a slight excess of semicarbazide acetate and pour into water. Collect the precipitated semicarbazones and dry the... 

Addition of solids to stirred liquids, 68 Addition tubes, 51 two-way, 51 three-way, 51 Adipic acid, 489, 494 Adipic dialdehyde, 892 Adsorbents for chromatographic adsorption, 159, 160... 

Various cyclitols (and acyclic polyols) have been desynunetrized by formation of dispoke intermediates. (See for example, Vol. 28, p. 237, ref. 115). L-Chiro-inositol can be converted to the silyl derivative 67 in which the trans-diol units are protected on reaction with l,3-dichloro-l,l,3,3-tetraisopropylidisiloxane (TipsQ). Compound 67 was further converted into conduritol B epoxide and its thioepoxide analogue. The conversion of some tetra-O-substituted myo-inosi-tols into adipic dialdehyde derivatives is mentioned in Chapter IS. 

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