Addition reactions Alkenes Alkynes Dienes Ketones

Hydrocyanation is the formal addition of hydrogen cyanide to alkenes. alkynes, and dienes to yield nitriles. These reactions can be catalyzed by various copper, cobalt, nickel and palladium catalysts modified with phosphanes and phosphites and/or Lewis acids. Hydrocyanation of carbonyl groups in aldehydes and ketones is covered in Section D.l.3.7. 

Abstract In the present chapter we discuss transition-metal-catalyzed phosphorus-hydrogen (P-H) bond addition to the triple bond of alkynes and to the double bond of alkenes, dienes, imines, aldehydes and ketones. Main attention is paid to highlight the factors responsible for development of highly efficient catalytic systems and to carry out the addition reaction with high stereo-, regio- and enantioselectivity. 

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