Adamantylimido complexes

Grubbs and coworkers studied a series of Ru-based catalysts and identified two lead catalysts for alkene cross metathesis that could provide the desired hetero-coupled product with high Z-selectivity for the resulting alkene moiety (Fig. 39) [91-93]. Comparably, Hoveyda and coworkers developed a number of Mo-based catalysts that enabled the selective synthesis of Z-alkenes [94, 95]. They successfully demonstrated that the novel molybdenum adamantylimido complexes (catalysts 154-156) could promote ring opening/cross metathesis (ROCM) of oxabicycle (157 or 158) in good yield and excellent Z-selectivity (Fig. 40) [96]. These elegant studies paved the way to develop further more effective catalysts for Z-selective alkene metathesis and utilize these methods for the synthesis of complex natural products. 

Bis(adamantylimido) compounds, with monomeric chromium(VI) complexes, 5, 348 Bis(alkene) complexes conjugated, Rh complexes, 7, 214 mononuclear Ru and Os compounds, 6, 401 -02 in Ru and Os half-sandwich rj6-arenes, 6, 538 with tungsten carbonyls and isocyanides, 5, 685 Bis(u-alkenylcyclopentadienyl) complexes, with Ti(II), 4, 254 Bis(alkoxide) nitrogen-donor complexes, with Zr(IV), 4, 805 Bis(alkoxide) titanium alkynes, in cross-coupling, 4, 276 Bis(alkoxo) complexes, with bis-Cp Ti(IV), 4, 588 Bis[alkoxy(alkylamino)carbene]gold complexes, preparation, 2, 288... 

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