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Acyl related factors

Chemical acylation of tylosin subsequently yielded a larger series of esters from which 4"-0-(4-methoxyphenylacetyl)tylosin (15) Figure 5.6) has emerged to the stage of preclinical studies due to its activity against certain resistant organisms and its improved metabolic stability [78-80], Several tylosin-related factors have also been acylated by chemical and biochemical methods [81-84], In addition to esters, 4"-0-alkyl and 4"-deoxy derivatives of tylosin have been prepared, but none was superior to compound (15) [85],... [Pg.273]

See other pages where Acyl related factors is mentioned: [Pg.97]    [Pg.102]    [Pg.93]    [Pg.97]    [Pg.102]    [Pg.564]    [Pg.208]    [Pg.375]    [Pg.203]    [Pg.416]    [Pg.624]    [Pg.234]    [Pg.548]    [Pg.230]    [Pg.2]    [Pg.399]    [Pg.168]    [Pg.747]    [Pg.958]    [Pg.103]    [Pg.323]    [Pg.1149]    [Pg.104]    [Pg.85]    [Pg.563]    [Pg.265]    [Pg.504]    [Pg.698]    [Pg.85]    [Pg.217]    [Pg.65]    [Pg.170]    [Pg.441]    [Pg.289]    [Pg.889]    [Pg.10]    [Pg.386]    [Pg.96]    [Pg.72]    [Pg.452]    [Pg.1001]    [Pg.887]    [Pg.559]    [Pg.652]    [Pg.35]    [Pg.283]    [Pg.267]    [Pg.104]    [Pg.356]    [Pg.176]   
See also in sourсe #XX -- [ Pg.37 , Pg.289 ]



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Relation factors

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