Acyl dehydrogenases

The four reactions of (3-oxidation are catalyzed by sets of enzymes that are each specific for fatty acids with different chain lengths (see Table 23.1). The acyl dehydrogenases, which catalyze the first step of the pathway, are part of an enzyme family that have four different ranges of specificity. The subsequent steps of the spiral use enzymes specific for long- or short-chain enoyl CoAs. Although these enzymes are structurally distinct, their specificity overlaps to some extent. 

Chemiosmotic and Conformational Coupling Fatty Acid Oxidation 54 Acyl Dehydrogenases Crotonase... 

The degradation reactions of methylbutyryl CoA are again catalyzed by the enzymes that are involved in the oxidation of the straight-chain fatty acids acyl dehydrogenase, crotonase, hydroxyacyl dehydrogenase. Only the last step of the sequence of reactions requires a specialized enzyme, ketoacyl thiolase. The products of that reaction are propionic acid and acetyl-CoA. 

Acyl dehydrogenase protein of unknown function DUF35 1526523-1527299... 

The three acyl dehydrogenases which are involved in this reaction are named according to the length of the carbon chain of the compound reacting most rapidly. All these enzymes contain FAD. An electron-transferring fiavoproteln (ETF) is interposed between the dehydrogenase and some components of the respiratory chain, e.g. non-heme iron, coenzyme Q or cytochrome b. 

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