Acyl chlorides organocadmium compounds

The most common application of organocadmium compounds has been in the preparation of ketones by reaction with acyl chlorides. A major disadvantage of the use of organocadmium reagents is the toxicity and environmental problems associated with use of cadmium, and this has limited the recent use of organocadmium reagents. 

The successful conversion of polystyrene-bound acyl chlorides into ketones by treatment with organocadmium compounds has also been reported (Entry 4, Table... 

Lithium bromide [1, 604, before references]. This halide markedly promotes the reaction of an organocadmium compound with acyl chlorides (but not with ketones). The effect was used to advantage in the synthesis of a-oxo esters.8... 

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