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Acyl chlorides, electrophilic fluorination

Some more exotic electrophilic reagents have been applied successfully to thiophens. Thus, pentafluorobenzenesulphenyl chloride reacts with thiophen in ether in the presence of catalytic amounts of SnCl to give 2-pentafluorophenyl-thio-thiophen. Thiophen and 2-methylthiophen give trifiuoromethylthio-derivatives with trifluoromethanesulphenyl chloride in chloroform in the presence of pyridine. Electron-deficient aromatics such as 2,5-bis(trifluoromethylthio)-thiophen react with trifluoromethanesulphenyl chloride, in the presence of trifluoromethanesulphonic acid as catalyst, to give mainly the 3-chloro-derivative. Fluorinated immonium salts (103), obtained by the action of boron trifluoride on a-fluorinated amines, can be used for fluorinated acylation of... [Pg.258]

See other pages where Acyl chlorides, electrophilic fluorination is mentioned: [Pg.740]    [Pg.154]    [Pg.90]    [Pg.193]    [Pg.881]    [Pg.493]    [Pg.1429]    [Pg.16]    [Pg.184]    [Pg.184]   
See also in sourсe #XX -- [ Pg.1355 ]



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Acyl chlorides

Acyl chlorides, electrophilic

Acyl electrophile

Acylation acyl chlorides

Acylation, electrophilic

Electrophiles acylation

Electrophilic fluorinating

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