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Activity-based probes functional elements

In their most basic form, activity-based probes consist of three distinct functional elements (Figure 2.1) a reactive group for covalent attachment to the enzyme, a linker region that can modulate reactivity and specificity of the reactive group, and a tag for identification and purification of modified... [Pg.34]


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Activating function

Activation function

Active elements

Active functional

Activity-based probes

Base function

Elemental base

Function-based

Functional activation

Functional activity

Functional element

Functions activity

Probe function

Probes activity

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