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Actinomycin, conformation

Actlnomvcin D - Kinetic studies with actinomycin D (act-D) in transplanted leukemic mice showed that a single dose provided cytotoxic concentrations for up to 24 hours,The characteristics of act-D resistance in L5178Y cells show that alterations in membrane composition and conformation in the drug-resistant subline accounts for the observed changes in the permeability of this drug.91 Act-D enhances the toxicity of morphine by increasing brain permeability. ... [Pg.134]

See other pages where Actinomycin, conformation is mentioned: [Pg.369]    [Pg.173]    [Pg.443]    [Pg.766]    [Pg.270]    [Pg.320]    [Pg.110]    [Pg.31]    [Pg.441]    [Pg.360]    [Pg.369]    [Pg.100]    [Pg.103]    [Pg.231]    [Pg.226]    [Pg.140]    [Pg.144]    [Pg.145]    [Pg.476]    [Pg.150]    [Pg.430]    [Pg.188]   
See also in sourсe #XX -- [ Pg.13 , Pg.14 ]



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