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Acid-base cluster hypothesis

Fig. 5.11. Acid-base cluster hypothesis. The cluster of acidic residues and basic residue is indicated on the upper portion of the figure. Fq is located on the left side where FT flux is transferred to the cluster. The movement of three protons from three NHj to three COO results in the charge neutralization, which causes conformational change to release tightly bound A, /S, y bidentate ATP-Mg complexes. After the energy is used up, three COOH s are dissociated and protons are released into the matrix side because of their pAT. Three NHj are protonated from the Fq side. The formation of ATP takes place without added energy, via in-line nucleophilic substitution (SNj) of O" of ADP to the P of inorganic phosphate. For details, refer to the text. Fig. 5.11. Acid-base cluster hypothesis. The cluster of acidic residues and basic residue is indicated on the upper portion of the figure. Fq is located on the left side where FT flux is transferred to the cluster. The movement of three protons from three NHj to three COO results in the charge neutralization, which causes conformational change to release tightly bound A, /S, y bidentate ATP-Mg complexes. After the energy is used up, three COOH s are dissociated and protons are released into the matrix side because of their pAT. Three NHj are protonated from the Fq side. The formation of ATP takes place without added energy, via in-line nucleophilic substitution (SNj) of O" of ADP to the P of inorganic phosphate. For details, refer to the text.
Acid base cluster hypothesis in proton motive ATP synthesis... [Pg.178]

See other pages where Acid-base cluster hypothesis is mentioned: [Pg.176]    [Pg.180]    [Pg.176]    [Pg.180]    [Pg.220]    [Pg.348]    [Pg.574]    [Pg.33]    [Pg.212]    [Pg.185]    [Pg.334]    [Pg.334]    [Pg.133]    [Pg.68]    [Pg.155]    [Pg.34]    [Pg.198]    [Pg.286]    [Pg.44]    [Pg.649]   
See also in sourсe #XX -- [ Pg.176 , Pg.177 , Pg.180 ]



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