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Aciculites orientalis

H2N0C- C02H Sponge -Aciculites orientalis Acicuiitins and acicuiitamides - antifungai peptides 14, 75... [Pg.39]

The lithistid sponge Aciculites orientalis contains three cyclic peptides, aciculitins A-C (130-132), that are identical except for homologous lipid residues [149]. The aciculitins consist of a bicychc peptide that contains an unusual histidino-tyrosine bridge. Attached to the bicyclic portion are Ci3-Ci5-dihydroxy-4,6-dienoic acids bearing D-lyxose at the C-3 position. The paper also reports the structures of the two artifacts aciculitamides A and B obtained earlier from the same sponge. The aciculitins inhibited the growth of Candida albicans and are cytotoxic toward the HCT-116 cell line. [Pg.1214]

See other pages where Aciculites orientalis is mentioned: [Pg.16]    [Pg.34]    [Pg.293]    [Pg.1003]    [Pg.1210]    [Pg.16]    [Pg.34]    [Pg.293]    [Pg.1003]    [Pg.1210]   
See also in sourсe #XX -- [ Pg.26 , Pg.1214 ]

See also in sourсe #XX -- [ Pg.1214 ]



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