Acetylsalicylic acid chemical structure

Chemical Name acetylsalicylic acid Chemical Structure see Figure 60.1... 

Only four years after Kekule proposed the ring structure for benzene, and before the configuration of salicylic acid was established, Kraut concluded on the basis of sound chemical evidence that the products obtained on heating acetylsalicylic acid possess chain structures formed through intermolecular esterification. He assigned the dimeric and tetrameric formulas... 

Figure 1.13. Chemical structure of salicin, salicylic acid and acetylsalicylate...

Therapeutic Function Analgesic, Antipyretic, Antiinflammatory Chemical Name 2-(Acetyloxy)benzoic acid Common Name Acetylsalicylic acid Structural Formula ... 

Figure 2.2 The chemical structure of aspirin (acetylsalicylic acid) is shown here.

The traditional method of drag development, at least in this century, has been to develop leads by first using, and then by isolating and identifying, the active chemical constituents from natural products, some of which may have been medicinally in use since antiquity. With the advent of modem organic chemistry some of these purified compounds were used directly (e.g., morphine, cocaine, atropine, quinine), and, once their chemical structures were ascertained, they became leads for hoped-for chemical modifications to achieve improved efficacy, less toxicity, or, at least, higher potency (e.g., dihydromorphinone, homatropine, acetylsalicylic acid). 

Fig. la-e. Chemical structures of (a) sodium benzoate, (b) salicylic acid, (c) acetylsalicylic acid, (d) 4-hydroxybenzoic acid, and (e) tartrazine... 

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