Acetylcholinesterase inhibitors organophosphate nerve agents

Although bicyclophosphates do not inhibit acetylcholinesterase, they exhibit a synergistic toxic effect with materials that do. Individuals who have had previous exposure to cholinesterase inhibitors such as nerve agents and commercial organophosphate or carbamate pesticides may be at a greater risk from exposure to bicyclophosphates. 

GF is a highly toxic nerve agent. It is a potent inhibitor of acetylcholinesterase and a neurotoxicant. The toxic symptoms are characteristics of sarin and other similar organophosphates. The toxicity is lower than GA, GB, GD, and VX. 

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