Acetylation amines and

Many gas chromatographic methods for amphetamine have been developed since then, most of which include a recommended internal standard such as N,N-dimethylaniline, phenethylamine, and di-phenylamine. These methods also include the formation of derivatives such as the acetylated amines and the ketone derivative of amphetamine as a further check on identity. 

Nature employs nucleophilic aQ l aubstitntion reactioiLs in the biosynthesis of many molecules, using thiol eaters for the purpose. Acetyl coenzyme A lavotyl C oA> ia a complex thiol ester that i- employed in living sj stcms to acetylate amines and alcoliola. 

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