Acetyl cannabispirol

In their next study, Shoyama and Nishioka isolated new spirocom-pounds cannabispirol and acetyl cannabispirol. This is in addition to the already known cannabispirone and cannabispirenone from a Japanese hemp variety. The two scientists included them in their biogenetic schema alongside the cannabinoid acids. In a further study, Shoyama et al. dealt with the biosynthesis of propylcannabinoid acids by in vitro incubation with raw enzyme solution from three species of Cannabis sativa KL. A biogenetic schema is presented illustrating the relationship between methyl, propyl and pentyl cannabinoid acids. 

Shoyama Y, Nishioka I, Cannabis. 13. 2 New spiro-compounds, cannabispirol and acetyl cannabispirol, Chem Pharm Bull 26 3641—3646, 1978. 

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