Acetophenone 3,5-dibromo-4-hydroxy

Bromo-2-nitropropane-1,2-diol 2-bromo-4-hydroxy-acetophenone l,2-Dibromo-2,4-dicyanobutane 2,2-dibromo-3-nitrilopropionamide 3.5-Dimethyl tetrahydro-2H-l,3,5-thiadiazine-2-thione disodium ethylene) (1,5-Pentanedial) 2-hydroxypropyl... 

Also obtained by reaction of sodium iodide on 3,5-dibromo-2-hydroxy-a,a,a-tribromo-acetophenone in acetic acid-dioxane-hydrochloric acid mixture (50%) [1818]. 

Preparation by action of bromine with 3,5-dibromo-2-hydroxy-acetophenone in refluxing acetic acid for 2.5 h (55%) [4382]. 

Preparation by bromination of 3,5-dibromo-4-hydroxy-acetophenone in chloroform [4384 386], (79%) [4386]. 

Claimed to be prepared from 2-hydroxyacetophe-none or 5-bromo-2-hydroxyacetophenone by reaction of bromine in glacial acetic acid and from 2-hydroxy-a-bromo-acetophenone by reaction ofbro-mine in 50% aqueous acetic acid (quantitative yields) (m.p. 107°) [4406], No proof of structure was provided [4407]. Actually, it probably concerns 3,5-dibromo-2-hydroxyacetophenone(m.p. 108° [4408], 108-109° [4386]), as the use of acetic acid as solvent favonrs the aromatic ring bromination. 

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