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Acetaminophen suppositories

Scale (mg/suppository) Item Material Name Quantity/1000 Suppositories (g) [Pg.97]

Transfer about one third of step 1 to a Becomix vessel through filter sieves set the temperature to 60°C. [Pg.97]

Load item 1 in step 4 and mix at 10 rpm and homogenize at speed I for 10 minutes maintaining the temperature of 50°-55°C under vacuum as above to make a smooth slurry. [Pg.97]

Transfer balance quantity of item 2 from step 1 into step 5 through filter sieve, set the temperature at 50°C and speed at 10 rpm, homogenize at speed II and under vacuum for 10 minutes. [Pg.97]

Handbook of Pharmaceutical Manufacturing Formulations Semisolid Products [Pg.98]

ACETAMINOPHEN SUPPOSITORIES 650MG ADULT RECTAL I.S. 100/PACKAGE 6505011677283 PG 37,98 ... [Pg.404]

All the above mentioned polymers have been evaluated mainly for application in the intestine. Finally, the last part of the gastrointestinal tract, the rectum should also be mentioned as a suitable site for delivery and fast absorption of therapeutics. Kim et al. [88] developed an in situ gelling and mucoadhesive acetaminophen liquid suppository prepared with poloxamers and sodium alginate. It was found that this particular formulation of acetaminophen in humans resulted in shorter T ax and higher maximum plasma concentrations of dmg (C ax) than the conventional acetaminophen suppositories. [Pg.186]

Acetaminophen (paracetamol) has good analgesic efficacy in toothaches and headaches, but is of little use in inflammatory and visceral pain. Its mechanism of action remains unclear. It can be administered orally or in the form of rectal suppositories (single dose,... [Pg.198]

Phenol Antimicrobial preservative disinfectant (not oral) Camphor, menthol, thymol, acetaminophen, phenacetin, chloral hydrate, phenazone, ethyl aminobenzoate, methenamine, phenyl salicylate, resorcinol, terpin hydrate, sodium phosphate, or other eutectic formers. Phenol also softens cocoa butter in suppository mixtures... [Pg.170]

Choi HK, Oh YK, Kim CK. In-situ gelling and mucoadhesive liquid suppository containing acetaminophen enhanced bioavailability. Int J Pharm 1998 165 23-32. [Pg.214]

J. J. Bergh and A. P. Lotter, A stability-indicating gas-liquid chromatographic method for the determination of acetaminophen and aspirin in suppositories, Drug Dev. Ind. Pharm., 10 127 (1984). [Pg.218]

Tablets, granules, suspension Amiodarone hydrochloride HPLC Extracted with AcOH-H20 (15 85), low-actinic flasks Bondapak Clg 5 mA/PlCB5, pH 3,5 w/AcOH-MeOH (9 1) 230 nm acetaminophen TLC [1], GC [2], stability [1104] suppositories [155,175] [152]... Tablets, granules, suspension Amiodarone hydrochloride HPLC Extracted with AcOH-H20 (15 85), low-actinic flasks Bondapak Clg 5 mA/PlCB5, pH 3,5 w/AcOH-MeOH (9 1) 230 nm acetaminophen TLC [1], GC [2], stability [1104] suppositories [155,175] [152]...
McEvoy, E., Donegan, S., Power, J., Altria, K.D. Optimisation and validation of a rapid and efficient microemulsion liquid chromatographic (MELC) method for the determination of paracetamol (acetaminophen) content in a suppository formulation. J. Pharm. Biomed. Anal. 44, 137-143 (2007)... [Pg.199]

Pluim MA, Wegener JT, Rupreht J, Vulto AG. Tramadol suppositories are less suitable for post-operative pain relief than rectal acetaminophen/codeine. Eur J Anaesthesiol 1999 16(7) 473-8. [Pg.3475]

Almodovar RA, Rodriguez RA, Rosario O. Inverse supercritical extraction of acetaminophen from suppositories. J Pharm Biomed Anal 1998 17 89-93. [Pg.577]

Choi H, Jung J, Ryu J et al (1998) Development of in situ-gelling and mucoadhesive acetaminophen liquid suppository. Int J Pharm 165 33 4... [Pg.226]

Ease of use, availability acetaminophen is a readily available over-the-counter medicine. It is available in many different formats (tablet, caplet, liquid suspension, suppository) for self-medication. [Pg.257]

See other pages where Acetaminophen suppositories is mentioned: [Pg.566]    [Pg.7]    [Pg.313]    [Pg.97]    [Pg.98]    [Pg.98]    [Pg.566]    [Pg.566]    [Pg.7]    [Pg.313]    [Pg.97]    [Pg.98]    [Pg.98]    [Pg.566]    [Pg.192]    [Pg.186]    [Pg.314]    [Pg.213]    [Pg.186]    [Pg.103]    [Pg.1182]    [Pg.19]    [Pg.565]    [Pg.213]    [Pg.186]    [Pg.1447]    [Pg.93]    [Pg.28]    [Pg.277]   
See also in sourсe #XX -- [ Pg.97 ]



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