Accelerator mass spectrometry absolute bioavailability

Sarapa, N., Hsyu, P. H., Lappin, G., and Gamer, R. C. (2005). The application of accelerator mass spectrometry to absolute bioavailability studies in humans Simultaneous administration of an intravenous microdose of 14C-nelhnavir mesylate solution and oral nelhnavir to healthy volunteers. J. Clin. Pharmacol. 45 1198-1205. 

Miyaji, Y., Ishizuka, T., Kawai, K., Hamabe, Y., Miyaoka, T., Oh-Hara, T., Ikeda, T., Kurihara, A. (2009) Use of an intravenous microdose of C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry. Drug Metabolism and Pharmacokinetics, 24(2), 130-138. 

---

See also in sourсe #XX -- [ , , ]

---