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Acanthodendrilla antifungal activity

An Acanthodendrilla sp. from Japan contained ten steroidal sulfates, acanthosterol sulfates A-J (561-570). Acanthosterol sulfates I (569) and J (570) showed antifungal activity against Saccharomyces cervisiae and its mutants [463]. Clathsterol (571), was isolated from the Red Sea sponge Clathria sp. The structure was established mainly by interpretation of spectral data and a chemical transformation. Clathsterol (571) was active against HIV-1 reverse transcriptase (RT) at a concentration of 10 iM [464]. Toxadocia zumi contains three sterol sulfates (572-574) that are antimicrobial, cytotoxic, ichthyotoxic and larvicidal [465]. [Pg.702]

See other pages where Acanthodendrilla antifungal activity is mentioned: [Pg.704]   
See also in sourсe #XX -- [ Pg.702 ]

See also in sourсe #XX -- [ Pg.28 , Pg.702 ]



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