A-Ketocarbothioates

Methylthiomethyl p-tolyl sulfone 257 was shown to react with various esters in the presence of excess NaH, affording compounds 263 which, upon reduction with NaBH4 and further treatment with alkali, can be converted to the corresponding aldehydes344. Oxidation of 263 with hydrogen peroxide gives S-methyl a-ketocarbothioates 264335. 

Ketene thioacetals 619 a-Ketoacylamides, synthesis of 615 a-Ketocarbothioates 635 a-Ketocycloalkyl sulphoxides, synthesis of 261... 

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See also in sourсe #XX -- [ ]

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