A alaninals

Common Name /3-(3,4-dihydroxyphenyl)-a-alanine 2-amino-3-(3,4-dihydroxyphenyl)pro-panoic acid... 

Fig. 2. Agents controlling the opening of Cl -channels. The structural formula, the name, the respeetive Cl -channel, and an appropriate reference are provided. (A) Note the similarity of GABA, taurine, and P-alanine. Note also that DPC and its analogues such as NPPB contain a -alanine backbone. (B) The structure of torasemide comes close to both DPC and furosemide or buraetanide. It blocks the Na ZCPK" -cotransporter with very high affinity and with lesser affinity also the TAL-Cl -channel. Note that IAA-94 is related to phenoxyaeetic acids (e.g., ethacrynic acid). Amidine is related to IAA-94 but it has a positive net charge. Amidine as well as IAA-94 block the ICOR channel at around lO mol/1 [63].

Amino acids containing nucleobases like uracil and adenine, as well as imidazole, such as / -(uraciM-yl)-a-alanine, j5-(adenin-9-yl)-a-alanine, and j8-(imidazol-l-yl)-a-alanine, can also be polycondensed by CDI in aqueous imidazole buffer solution at pH 6.8 at 0 °C. The polycondensation leads to low conversion (yields of polymer 1% after four days), but pure polypeptides resulted from the reaction. Thus, compared to other alternative procedures for polycondensation, that using CDI proved to be the most effective 503... 

Figure 2.9. Amino acid sequences of human defensins. The conserved positions of six cysteine residues are shown in hatched boxes. Abbreviations A, alanine C, cysteine D, aspartic acid E, glutamic acid F, phenylalanine G, glycine H, histidine I, isoleucine K, lysine L, leucine M, methionine N, asparagine P, proline Q, glutamic acid R, arginine S, serine T, threonine V, valine W, tryptophan Y, tyrosine.

Fig. 12 A- D. Separation of a mixture of cyctochromes C from various sources in 20 pm i. d. capillary columns. (Reprinted with permission from [78]. Copyright 2000 Elsevier). Conditions A bare capillary B unetched C18 modified capillary C,D etched C18 modified capillary, total column length 50 cm, active length 25 cm, voltage 30 kV (A,B,C) and 15 kV (D), mobile phase 60 mmol/1 a-alanine and 60 mmol/1 lactic acid pH 3.7, detection at 211 nm, pressurized injection for 2 s using vacuum...

Fic. 1. The amino acid sequences of calf histones H2A (Yeoman et al., 1972 Sau-tiere et al., 1974) and H2B (Iwai et al., 1972). A one-letter code is used A, alanine R, arginine N, asparagine D, aspartic acid C, cysteine E, glutamic acid Q, glutamine ... 

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