A -acetylvaline

The asymmetric cyclopalladation of dimethylaminomethylferrocene takes place in the presence of an optically active carboxylic acid (e.g, A -acetylvaline), giving the cyclopalladation product 478 in 78% ee, from which optically active ferrocene derivatives were prepared[434]. 

The differences in energy found for the heterochiral dimers vs. the homochiral ones (between 2.9 and 10.1 kJ mol ) should lead to very different populations of the given dimers thus, it should be possible to observe these differences with a variety of standard techniques. In this sense, the homo and heterochiral dimers of A-acetylvaline f-butyl ester [131] and dihydroquinones [132] have been observed by NMR spectroscopy. 

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