7V-methyl

V-Methyl-7V-nitroso-p-toluenesulfonamide (diazald) [80-11-5] M 214.2, m 62 . Crystd from benzene by addition of pet ether, store in a refrigerator. 

V-Methyl-7V-trimethylsilylacetamide [7449-74-3] M 145.3, b 48-49 /llmm, 84 /13mm, 105-107 /35mm (solid at room temp), d 0.90, n 1.4379. Likely impurity is Et3N.HCl which can be detected by its odour. If it is completely soluble in C6H6, then redistil, otherwise dissolve in this solvent, filter and evaporate first in a vacuum at 12mm then fractionate, all operations should be carried out in a dry N2 atmosphere. [J Am Chem Soc 88 3390 7966 Chem Ber 96 1473 7965.]... 

Amino-4,6-dimethyl-3-oxo-3//-phenoxazine-l,9-dicarboxylic acid also named actinocin is the chromophor of the red antineoplastic chromopeptide aetinomyein D (formula A). Two cyclopenta-peptide lactone rings (amino acids L-threonine, D-valine, L-proline, sarcosine, and 7V-methyl-L-valine) are attached to the carboxy carbons of actinocin by two amide bonds involving the amino groups of threonine. 

Finke, P. E., Oates, B., Mills, S. G., MacCoss, M., Malkowitz, L., Springer, M. S., Gould, S. L., DeMartino, J. A., Carella, A. Carver, G., et al. (2001). Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4 synthesis and structure—Activity relationships for l-[7V-(Methyl)-7V-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(7V-(alkyl)-7V-(benzylox-ycarbonyl)amino)piperidin-l-yl)butanes. Bioorg. Med. Chem. Lett. 11 2475-2479. 

V-methyl-7V-(o-aminophenyl)anthranilic acid methyl ester... 

C H,, N203 85660-33-9) see Nomifensine 7V-methyl-lV-(2-nitrobenzyl)phenacylamine (C (,H 9N203 102436-67-9) see Nomifensine 2-methyl-5-nitro-4,6-dihydroxypyrimidine (C5H5N3O4 53925-27-2) see Moxonidine 2-methyl-5-nitroimidazole... 

C19H24N2O 70708-28-0) see Triprolidine 7V-methyl-2-phenylsuccinamic acid (C ]H,3N03 73294-89-0) see Phensuximide (25-trans)-4-[[(4-methylphenyl)sulfonyl]oxy]-l, 2-pyrroli-dinedicarboxylic acid l-(l,l-dimethylethyl) 2-(phenylme-thyl) ester... 

Methylmagnesium bromide, 55, 63 Methyl maleate, 56, 63 Methyl mercaptan, 56, 73 Methyl 4-methoxybenzoate, 55, 40 Methyl 5-methyl-2-hexynoate, 55, 76 7V-Methyl-2-methylthiothiazolium iodide,... 

The l-(7V-methyl)benzimidazolyl-3-benzimidazolyl-2-oxapropane ligand (107) shows coordination through the N20 donor set of the ligand, a water molecule and an acetonitrile to give a five-coordinate distorted trigonal-bipyramidal metal center.123 This contrasts with the behavior of the related thiapropane ligand that forms bidentate complexes with zinc. 

Water soluble iron porphyrins [Fem(TPPS)(H20) ]3-330 and [Fem(TMPy)(H20)2]5+ 331 332 (TPPS = maso-tetrakis(/ -sulfonatophenyl)porphyrin, TMPyP = / /e.vo-tetrakis(7V-methyl-4-pyridi-nium)porphyrin331 or maso-tetrakis (A -methyl-2-pyridinium)porphyrin332 dications) act as effective electrocatalysts for the reduction of nitrite to ammonia in aqueous electrolytes (Equation (64) Ei/2= 0.103 V vs. SCE at pH 7), with NH2OH or N20 also appearing as products depending on the reaction conditions. Nitric oxide then ligates to the iron(III) porphyrin to form a nitrosyl complex [Fen(P)(NO+)] (P = porphyrin) as intermediate. 

When l,2,3,4-tetrakis(4-pyridinyl)cyclobutane is treated with ethyl chloroformate in the presence of ethyldiisopropylamine, radialene 74a is formed and can be isolated as red crystals. Addition of AgBEt to a red solution of 74a results in an immediate color change to deep blue caused by the formation of the dicationic species 75a (equation 5)43. Undoubtedly, the tetrapyridiniocyclobutane 73a is an intermediate in the formation of 74a. By way of contrast, the fourfold deprotonation of the analogous tetrakis(7V-methyl-4-pyridinyl)cyclobutane (73b) did not succeed in the presence of oxygen. Treatment with NaH/EtOH in the presence of oxygen produced the dication 75b, which could be reduced to the [4]radialene only electrochemically44. Deprotonation of 73b with sodium hydride... 

Cryptopine-type indole alkaloid bumamicine (572) has been synthesized from geissoschizine methyl ether (31) (287). In the first step, geissoschizol (34) was prepared, and then cleavage of the C/D ring fusion was carried out by means of ethyl chloroformate. Finally, C-3 carbonyl and 7V-methyl groups were developed by simple oxidation, reduction, and repeated oxidation steps. 

We now consider 7V-methyl-2-(3-pyridyl)pyrrolidine (7), also known as the alkaloid nicotine. Parallelling our discussion of coniine, we find in Kharasch and Domalski the nearly century-old enthalpy of formation for the liquid of 39 kJmol-1. Is this value plausible With (liquid, tert/R, R1, R2) necessary to transform a tertiary amine into the corresponding hydrocarbon24, we would conclude that the enthalpy of formation of liquid l-methyl-2-(3-pyridyl)cyclopentane (8, R = 3-Py) is ca —50 kJmol-1. To estimate the last datum in another way, we assume that equation 10 is essentially thermoneutral. 

Irradiation rraws-2-[3-(7V-methylamino)propyl] stilbene 89 results in the formation of 7V-methyl-l-benzyltetrahydro-2-benzazepine 90 as the only significant primary photoproduct (equation 26), which in turn undergoes secondary photochemical N-demethylation. The final mixture contains 90 (38%) and 91 (25%) at high (>95%) conversion. Intramolecular photoadditions of these (equations 24-26) secondary (aminoalkyl)-stilbenes are highly regioselective processes24. 

The first example of a counterthermodynamic one-way E - Z photoisomerization based upon intramolecular hydrogen bonding was reported for the 7V-methyl-3-(2-pyridyl)-propenamide systems. 

Synonyms BRN 0964788 CCRIS 3143 CE EINECS 207-531-9 7V-Methyl-2,4,6-tetranitro-aniline -Methyl-iV,2,4,6-tetranitrobenzenaniine Nitramine NSC 2166 Picrylmethyl-nitramine Picrylnitromethylamine Tetralit Tetralite Tetril 2,4,6-Tetryl Trinitrophenylmethyl-nitramine Trinitrophenyl-7V-methylnitramine 2,4,6-Trinitrophenylmethylnitramine 2,4,6-Trinitro-phenyl-A7methylnitramine UN 0208. 

Chemical/Physical. The following compounds were identified as metabolites in rice plants after treatment with chlorphenamidine 7V-(4-chloro-o-tolyl)-7V-methyl formamidine, 7V-formyl-4-chloro-o toluidine, and 4-chloro-o toluidine (Lizuka and Masuda, 1979). 

The change from 7V-methyl- (structure a of Scheme 6.29) to Al-isopropyl substitution (structure b) lowers the electron-transfer barrier (Nelsen 1997, p. 171). The p,p -phenylene-linked system (structure c) features fast electron transfer under comparable conditions. The cation-radical from the last bis-hydrazine is instantaneously localized in contrast to the cation-radical from tetramethyl-p-phenylenediamine, which is delocalized (Nelsen et al. 1996, 1997a, 1998b Valverde-Aguilar et al. 2006). 

Bis(7V-methyl-D-glucaminedithiocarbamate)iron(II) and bis(2,3-dithiopropane-l-sulfonate)-iron(II) react with 5-nitrosothiols with transfo of NO to iron. " ... 

V-Methyl-2-methyl-3-(benzotriazol-l-yl)propanamide (631), on treatment with two equivalents of butyllithium, forms a dianion that reacts with alkyl and benzyl halides, aldehydes, and ketones to give monosubstituted products (632) (Scheme 124). With ethyl / -toluate, however, a lactam (634) is formed. The alkylated derivatives (632) eliminate benzotriazole upon treatment with NaOEt to afford trisubstituted a,)8-unsaturated amides (633) <93JHC1261>. 

---