17a-Dichloroester soft steroids

Figure 15.11. Overlapping pharmacophore structures of corticosteroids, (a) Clobetasol propionate (in gray) and the soft corticosteroid loteprednol etabonate (26) (in black). The view is from the a side, from slightly below the steroid ring system, (b) Loteprednol etabonate (in black) and a 17a-dichloroester soft steroid (in gray). This view is from the (3 side, from above the steroid ring system.

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