These reactions follow first-order kinetics and proceed with racemisalion if the reaction site is an optically active centre. For alkyl halides nucleophilic substitution proceeds easily primary halides favour Sn2 mechanisms and tertiary halides favour S 1 mechanisms. Aryl halides undergo nucleophilic substitution with difficulty and sometimes involve aryne intermediates.  [c.283]

See pages that mention the term Raccmizalion : [c.111]    [c.87]    [c.1735]   
Organic syntheses Acrolein (0) -- [ c.82 ]